Searchable abstracts of presentations at key conferences on calcified tissues

ba0001oc1.3 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Size at birth is not associated with risk of hip fracture. results from two population-based cohorts

Byberg Liisa , Michaelsson Karl , Koupil Ilona

Early life growth has been suggested to influence bone health. However, the relationship with risk of hip fracture in old age has not been thoroughly investigated. We therefore studied the association between birth weight and hip fracture incidence after age 50 among 10 893 men and women (48% women) from the Uppsala Birth Cohort Study (UBCoS, born 1915–1929) and 1334 men from the Uppsala Longitudinal Study of Adult Men (ULSAM, born 1920–1924). Birth weight was collec...

ba0001oc1.4 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Intake and serum levels of α-tocopherol in relation to fractures in elderly women and men

Michaelsson Karl , Wolk Alicja , Byberg Liisa , Arnlov Johan , Melhus Hakan

Recent studies indicate a potential importance of the antioxidant α-tocopherol for bone and the development of sarcopenia. No longitudinal clinical fracture studies have been performed. We aimed to determine whether α-tocopherol intake or serum concentrations are associated with fracture risk in older women and men. We used data from two community-based cohorts, the Swedish Mammography Cohort (SMC; 61 433 women) and the Uppsala Longitudinal Study of Adult Men (ULSAM;...

ba0001pp379 | Osteoporosis: pathophysiology and epidemiology | ECTS2013

Where and when do hip fractures occur? A population-based study

Leavy Breiffni , Aberg Anna Cristina , Melhus Hakan , Mallmin Hans , Michaelsson Karl , Byberg Liisa

Purpose: To describe the timing and whereabouts of the hip fracture patient at the time of fracture in a population-based setting and to relate these factors with residential and health status, seasonal variation and snow-covered ground.Methods: We consecutively included 486 hip fracture cases (age ≥50 years) admitted to a Swedish Orthopedic Department during a 1-year period. Data concerning socio-demographic details, fall location, time of fractur...

ba0001pp381 | Osteoporosis: pathophysiology and epidemiology | ECTS2013

Impact of hip fracture on mortality and life expectancy

Michaelsson Karl , Nordstrom Peter , Nordstrom Anna , Garmo Hans , Byberg Liisa , Pedersen Nancy , Melhus Hakan

Several studies have shown a higher mortality after hip fracture but the reasons and the duration of the excess risk is not well understood. We aimed to determine whether there exists a higher mortality after hip fracture when controlling for genetic constitution, environmental and life-style risk factors, and comorbidity. All 286 identical Swedish twin pairs discordant for hip fracture (1972–2010) were identified by use of the National patient register and the Swedish tw...